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What is Generic Viagra (Sildenafil Citrate)?
Generic Viagra or Sildenafil Citrate is the first significant oral medication for the treatment of Erectile Dysfunction (ED). The medicine was originally developed as a cardiovascular medicine designed to improve blood flow in the vessels of the heart. However, during initial studies the medication was found to have a profound side effect. Individuals began to report a remarkable difference in their ability to achieve and maintain an erection. Further studies were completed and on March 27, 1998, the medication was approved by the FDA for the treatment of (ED).

How does this medication work?
Generic ViagraŽ is dispensed as a pill and ingested orally. Approximately 30-60 minutes later the drug is absorbed in the bloodstream. Viagra generic then functions as an inhibitor to an enzyme called phosphodiesterase type (PDE5) which is found primarily in the penis. By inhibiting PDE5, smooth muscle in the penis remains relaxed for a longer period. This allows for increased blood flow into the cavernous tissue of the penis thereby generating an erection. Generic Sildenafil Citrate is unique in that it increases a natural occurring process, therefore, only through sexual stimulation will an erection occur.

What is the appropriate dose?
The standard dose is 50mg one hour prior to sexual activity. However, if you are older than age 65 or have a serious kidney or liver disease some physicians will recommend starting with the minimal dose of 25mg. Generic ViagraŽ should not be taken more than once per any 24-hour period and doses should not exceed 100mg. The half-life of Generic drug for ViagraŽ, the time the drug remains effective after ingestion, is approximately four hours.

What clinical studies have been done?
This medication was administered to more than 3000 patients (age 19-87 years) with (ED) of various etiologies (organic, psychogenic or mixed) with a mean duration of 5 years. It demonstrated statistically significant improvement as compared to a placebo in all studies. In one particular study concerning the frequency of successful penetration during sexual activity and maintaining erection after penetration, 83% of these patients reported an improved erection verses 12% on a placebo medication.

How much time must surpass before Sildenafil Citrate is effective?
Viagra is rapidly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median time 60 minutes) of oral dosing on an empty stomach. Note: when ViagraŽ Generic is taken with a high fat content meal, the rate of effectiveness can be significantly diminished.

What are the side effects of Generic ViagraŽ? The side effects are relatively few and if they do occur, they are usually short lived. However, some patients have reported the following side effects:
  • Congestion
  • Diarrhea
  • Facial Flushing
  • Headaches
  • Urinary Tract Infections
  • Visual Changes (mild and temporary changes in blue/green colors or increased sensitivity to light)

What are precautions/warnings concerning this drug?
Men who are taking medicines that contain nitrates (Nitroglycerin) of any kind must never use Generic ViagraŽ. Patients should not take it even if you only take nitroglycerin medication occasionally. (Please see list of nitrates) There is also a potential for cardiac risk during sexual activity in patients with preexisting cardiovascular disease. Therefore, this medication should not be used in men where sexual activity is inadvisable because of their underlying cardiovascular status. Several medications are known to interact with Genric ViagraŽ. Therefore, one should inform their physician concerning all medications they are taking, including those medications acquired by a prescription as well as over the counter medicines. The use of Viagra offers no protection against sexually transmitted diseases, including HIV. Patients should continue to use protective measures necessary to guard against these diseases. In case of an overdose, call your physician immediately.




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